Meaning
A name that means something.
S"Pure, chosen, best friend." Safiyya bint Huyayy was a wife of the Prophet, of Jewish origin, who converted to Islam. The word also means "the most precious share of the spoils."
Etymology, in one line
Arabic root: ṣ-f-w — ص-ف-و, purity
Regional variants
"Safiyah" is the most common US spelling. "Safietou" is the Senegalese-American form.